Survivin (SVN) is a member of the inhibitor of apoptosis (IAP) protein family that promotes cellular proliferation and inhibits apoptosis. Overexpression of SVN is associated with autoimmune disease, hyperplasia, and tumors and can be used as a biomarker in these diseases. SVN is widely recognized as a tumor-associated antigen (TAA) and has become an important target for cancer diagnosis and treatment.
Read the full article: Survivn as a biological biomarker for diagnosis and therapy
By: Yuming Li, Wenshu Lu, Jiarun Yang, Mark Edwards and Shisong Jiang
Published in Expert Opinion on Biological Therapy on 21st June 2021